To measure the shear bond strength (SBS) of a dual-cured resin cement to human dentin under self-curing mode, and compare it with the SBS of two self-cured cements. The SBS of two self-cured resin cements (Super-Bond C&B, Sun Medical Co. Ltd, Kyoto, Japan (SB); C&B Cement, Bisco Inc., Schaumburg, IL, USA (CB)) and one dual-cured resin cement (NX3 Nexus, Kerr Corporation, Orange, CA, USA (NX)) were measured according to ISO 11405. All resin cements were used according to the manufacturers’ instructions to bond to the dentin of premolar teeth using a stainless-steel cylinder mold and allowed to self-cure. Shear bond strengths were measured after 1h and 24h storage in a humidified lightproof box at 37o C. Super-Bond C&B exhibited the highest bond strength at both 1h and 24h ((19.2 ± 2.8) MPa, (34.0 ± 5.1) MPa respectively) and the lowest was C&B Cement ((5.2 ± 1.1) MPa, (10.5 ± 2.8) respectively) (p≤0.05). The bond strength at 24h in all groups were significantly higher than at 1h. Resin cements with different chemical formulations yield significantly different bond strengths to human dentin. The self-cured acrylic resin cement showed the highest bond strength and should therefore be preferred in clinical situations where the photo-curing light cannot transmit through the restoration. Time after bonding increased the bonding performance of all resin cements.