Article information
Year 2020 Volume 70 Issue 1 Page 54-62
Title:
The Comparison of the Effect of Antacid and Remineralizing Agent on the Prevention of Enamel Surface Loss and Microhardness of Human Enamel Exposed to Hydrochloric Acid
Keyword(s):
Hydrochloric acid, Enamel surface loss, Microhardness, Antacid, Remineralizing agent
Abstract:
The aims of this study were to compare the effects of antacid and remineralizing agent on the prevention of
enamel surface loss and microhardness of enamel exposed to hydrochloric acid. Flat specimens on buccal enamel
surface of 60 extracted human premolar teeth were prepared. Each specimen was subjected to microhardness
measurement to obtain a baseline value. The specimens were allocated into 3 groups (n=20) consisting of the
treatments: antacid, remineralizing agent and control group. All specimens were exposed to hydrochloric acid for
2 minutes. Then the specimens were either immersed in antacid for 2 minutes or applied remineralizing agent for
3 minutes depending on the experimental groups. Finally, the specimens were immersed in artificial saliva for 24 hours.
The process was repeated for 5 cycles. The final microhardness and enamel surface loss were assessed. The data were
analyzed statistically with the level of significance at p<0.05. Using Paired T-test to compare baseline and final
microhardness within group, Welch ANOVA and Game-Howell multiple comparisons to compare baseline and final
microhardness between groups, One-way ANOVA and Post hoc Turkey’s test to compare enamel surface loss between
groups. The final microhardness of all groups was significantly lower than the baseline microhardness (p<0.001).
Compared to control group, the final microhardness was significantly higher when using antacid and remineralizing
agent (p=0.001 and 0.003 respectively) and the enamel surface loss was significantly lower when using antacid and
remineralizing agent (p<0.001 and 0.006 respectively). The final microhardness and enamel surface loss between
the antacid and remineralizing agent groups were not significantly different. From the result of this study, the effects
of antacid and remineralizing agent on the prevention of enamel surface loss and microhardness of human enamel
exposed to hydrochloric acid were not significantly different.