Objective: To evaluate the effects of surface treatments on the shear bond strength between acrylic denture teeth and resin composite. Materials and methods: In this study, 50 acrylic denture teeth were divided into 5 groups, 10 for each. For Group 1, the acrylic denture teeth were treated with Methyl methacrylate for 180 seconds. Group 2, the acrylic denture teeth were treated with Methyl methacrylate for 180 seconds and silane. Group 3, the acrylic denture teeth were treated with 37 % Phosphoric acid and Methyl methacrylate for 180 seconds. Group 4, the acrylic denture teeth were treated with 37 % Phosphoric acid, Methyl methacrylate for 180 seconds and silane. And group 5, the acrylic denture teeth were treated with air-abrasion, 37 % Phosphoric acid, Methyl methacrylate for 180 seconds and silane. All specimens were applied with bonding agent after the surface treatments. The resin composite was packed using a mold with a space of 3 mm in diameter and 3 mm in high. The specimens were incubated in a control humidity and temperature for 24 hours before the testing. The shear bond strength was tested with the SHIMADZU EZ-S Universal Testing Machine. The shear bond strength was analyzed by using One-Way ANOVA to determine the significant differences at p-value <0.05, and multiple comparisons of shear bond strength by using Turkey’s HSD. Failures mode was evaluated by randomly selecting 3 specimens from each group to investigated under the scanning electron microscope. Results: The averages shear bond strength of group 1 to 5 are 6.123 + 0.828, 6.012 + 0.893, 6.336 + 0.843, 6.173 + 0.876 and 20.901 + 0.851 MPa, respectively. Upon analysis using a One-Way ANOVA, there were no statistical differences shown in shear bond strength when comparing between Groups 1 to 4, but they were statistically significantly different when compared to group 5 (p<0.001). Once the specimens were evaluated under the scanning electron microscope, all groups were categorized under the failure modes as adhesive, with Group 5 showing the highest amount of surface roughness. Conclusion: The acrylic denture teeth that were treated with air-abrasion, 37 % Phosphoric acid, Methyl methacrylate for 180 seconds, silane and bonding agent, respectively, had the highest shear bond strength compared to the other groups with statistical significance. The surface roughness created by air abrasion so increased the surface area available for bonding.