Pit and fissure sealants have been effective in reducing occlusal caries but their effectiveness on partially erupted teeth may be precluded by difficulties with moisture control and tissue management during application. In preliminary studies, a bonding agent has been shown to bond adequately to etched enamel after salivary contamination. The objective of this study was to evaluate clinical retention of sealant bonding eruption of the first permanent molars in 3 months. Thirty-six teeth in twenty-one children were divided randomly into two groups: sealant was placed with or without the bonding agent. 3M™ Single Bond. After 3 months, the retention rate for the sealant with Single Bond adhesive were 88.89% full retention and 11.11% partial loss versus 77.78% full retention 22.22% partial loss for sealant without bonding agent and there was no total loss in both groups. The retention of two groups was compared using Fisher Exact test. The results show that there was no significant difference between the two groups in 3 months (p=0.24).Pit and fissure sealants have been effective in reducing occlusal caries but their effectiveness on partially erupted teeth may be precluded by difficulties with moisture control and tissue management during application. In preliminary studies, a bonding agent has been shown to bond adequately to etched enamel after salivary contamination. The objective of this study was to evaluate clinical retention of sealant bonding eruption of the first permanent molars in 3 months. Thirty-six teeth in twenty-one children were divided randomly into two groups: sealant was placed with or without the bonding agent. 3M™ Single Bond. After 3 months, the retention rate for the sealant with Single Bond adhesive were 88.89% full retention and 11.11% partial loss versus 77.78% full retention 22.22% partial loss for sealant without bonding agent and there was no total loss in both groups. The retention of two groups was compared using Fisher Exact test. The results show that there was no significant difference between the two groups in 3 months (p=0.24).