The aim of the pulp treatment in primary teeth is to preserve and maintain fully functional primary teeth
in the dental arch until the time of natural exfoliation. It is well studied that microorganisms are considered to be
a major cause of pulpal and periapical pathosis. Therefore, the primary goal of pulp treatment is to eliminate or
reduce microorganisms inside an infected root canal system. Root canal cleaning with irrigating solutions becomes
one of the standard protocol as it can remove microorganisms, tissue debris, and smear layer efficiently. Various
irrigating solutions have been suggested for pulp treatment in primary teeth. Different irrigants have distinct properties
and, thus, present with different advantages, disadvantages and limitations. In clinical practice, these properties
need to be considered, in particular, when using in pediatric patients. The objective of this article is, therefore, to
review the various irrigating solutions commonly used in pulp treatment in primary teeth in many aspects. The mechanisms of actions, effectiveness, and their side effects are discussed. This information would be useful for
clinicians to choose an irrigant during pulp treatment procedure.