Fibrin glue has been used as hemostatic agent, but the previous studies showed controversial results. The objective of this study was to find out whether fibrin glue could promote bone healing of extracted tooth sockets. Eight patients with bilateral impacted lower third molars were included in this study. After surgical removal of the impacted tooth, fibrin glue was applied on one side whereas the other side was designated as control. The radiographs were taken, scanned and analysed immediately and every one month following up until 5 months. The relative radiodensity of bone was expressed as the ratio between the measusred value of the tooth socket and dentine of second molar multiplied with 100. The radiodensity at immediately, 1, 2, 3, 4 and 5 months postoperative of the experimental sides were 77.96, 81.21, 81.47, 82.16, 84.67 and 86.31 respectively. The values of the control sides were 78.96, 77.02, 77.00, 78.86, 82.97 and 80.57 respectively. These results indicated the incresing of radiodensity along the postoperative time in the experimental sides, while there was no statistical difference of the radiodensity in the control sides as tested by repeated measure one-way ANOVA and multiple comparison test. The radiodensity of the experimental sides at 1, 2 and 5 months after operation were statistically significant greater than the control sides as tested by paired t-test. These findings were consisted to positive effect on bone healing. Therefore our results suggest that fibrin glue can promote tooth socket healing.