Artificial eruption (AE) is an orthodontic procedure aiming at assisting an impacted tooth to erupt and to align with adjacent teeth for functional and/or esthetic purposes. AE of multiple or poor prognosis impacted teeth is challenging and needs an interdisciplinary approach. The objective of this case report is to present the AE procedures and outcomes of two cases with complicated impacted dentition. The first patient had 3 high impacted maxillary anterior teeth of which self-eruption occurred after space in the dental arch was gained. The second patient had a tooth impacted in a poor prognosis position. The tooth was eventually brought into the arch after a series of attachment reposition and force direction design. All rescued teeth were well aligned with their adjacent teeth. Periodontal status was as healthy as their counterparts on the other side of the arch.