This case report presents a successful interdisciplinary dental treatment to manage edentulous spaces in a skeletal class III case using camouflage orthodontic treatment with autotransplantation of a tooth with complete root
formation, by four specialties: prosthodontics, endodontics, oral surgery, and orthodontics. The treatment plan included extraction of the mandibular left first premolar and the maxillary right first premolar as well as autotransplantation of the maxillary right first premolar into the maxillary left premolar edentulous area. The keys to success of the autotransplantation were: (1) endodontic treatment of the donor tooth prior to orthodontic tooth alignment with round wire, (2) preapplication of orthodontic force before extraction, (3) preparation of the recipient socket guided by the periapical radiograph and study casts, (4) preservation of the donor tooth in its own bleeding socket during trying in, and (5) the use of a short-term suture splint. Comprehensive orthodontic treatment was completed, with favourable results. The treatment time was 38 months. The transplanted tooth was in excellent condition for a porcelain crown restoration, but the patient declined the treatment. After seven years of follow-up, the transplanted tooth was still in good condition with no signs of inflammation, or root resorption. This article thoroughly discusses the decision making for the treatment sequence and appropriate approaches from each specialist.